Article
Rare Coding Variation and Risk of Intracerebral Hemorrhage.
Stroke - 1 Aug 2015
Radmanesh Farid, Falcone Guido J, Anderson Christopher D, McWilliams David, Devan William J, Brown W Mark, Battey Thomas W K, Ayres Alison M, Raffeld Miriam R, Schwab Kristin, Sun Guangyun, Deka Ranjan, Viswanathan Anand, Goldstein Joshua N, Greenberg Steven M, Tirschwell David L, Silliman Scott L, Selim Magdy, Meschia James F, Brown Devin L, Worrall Bradford B, Langefeld Carl D, Woo Daniel, Rosand Jonathan
Abstract excerpt
BACKGROUND AND PURPOSE: Intracerebral hemorrhage has a substantial genetic component. We performed a preliminary search for rare coding variants associated with intracerebral hemorrhage. METHODS: A total of 757 cases and 795 controls were genotyped using the Illumina HumanExome Beadchip (Illumina, Inc, San Diego, CA). Meta-analyses of single-variant and gene-based association were computed. RESULTS: No rare...
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