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Article

Chlamydia trachomatis virulence factor CT135 is stable in vivo but highly polymorphic in vitro.

Pathogens and disease - 1 Aug 2015

Bonner Christine, Caldwell Harlan D, Carlson John H, Graham Morag R, Kari Laszlo, Sturdevant Gail L, Tyler Shaun, Zetner Adrian, McClarty Grant

Abstract excerpt

Chlamydia trachomatis is an important human pathogen causing both ocular and sexually transmitted disease. Recently, we identified CT135 as an important virulence determinant in a mouse infection model. Results from CEL 1 digestion assays and sequencing analyses indicated that CT135 was much more polymorphic in high in vitro passage reference serovars than it was in clinical strains that had undergone limited...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26109550
DOI: 10.1093/femspd/ftv043
PMCID: PMC4852218

Genes

CEL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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