Article
Trp triad-dependent rapid photoreduction is not required for the function of Arabidopsis CRY1.
Proceedings of the National Academy of Sciences of the United States of America - 21 Jul 2015
Gao Jie, Wang Xu, Zhang Meng, Bian Mingdi, Deng Weixian, Zuo Zecheng, Yang Zhenming, Zhong Dongping, Lin Chentao
Abstract excerpt
Cryptochromes in different evolutionary lineages act as either photoreceptors or light-independent transcription repressors. The flavin cofactor of both types of cryptochromes can be photoreduced in vitro by electron transportation via three evolutionarily conserved tryptophan residues known as the "Trp triad." It was hypothesized that Trp triad-dependent photoreduction leads directly to photoexcitation of...
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