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Article

Hyperactivity of the Arabidopsis cryptochrome (cry1) L407F mutant is caused by a structural alteration close to the cry1 ATP-binding site.

The Journal of biological chemistry - 4 Aug 2017

Orth Christian, Niemann Nils, Hennig Lars, Essen Lars-Oliver, Batschauer Alfred

Abstract excerpt

Plant cryptochromes (cry) act as UV-A/blue light receptors. The prototype, Arabidopsis thaliana cry1, regulates several light responses during the life cycle, including de-etiolation, and is also involved in regulating flowering time. The cry1 photocycle is initiated by light absorption by its FAD chromophore, which is most likely fully oxidized (FADox) in the dark state and photoreduced to the neutral flavin...

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Identifiers

PMID: 28634231
DOI: 10.1074/jbc.M117.788869
PMCID: PMC5546031

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