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Article

The Role of Complement in Antibody Therapy for Infectious Diseases

14 Mar 2014

Abstract excerpt

The complement system is part of the innate immune system, eliciting central immunoregulatory functions. Detection of foreign surfaces is either achieved through complement-specific patternrecognition molecules or mediated by antigen recognition of antibodies. Immunoglobulin A (IgA), IgG, and IgM all have the potential to initiate a complement response, with the efficiency and response development closely related...

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PMID: 26105816
DOI: 10.1128/microbiolspec.aid-0015-2014

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