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Article

Using Plasmids as DNA Vaccines for Infectious Diseases

21 Nov 2014

Abstract excerpt

DNA plasmids can be used to induce a protective (or therapeutic) immune response by delivering genes encoding vaccine antigens. That naked DNA (without the refinement of coat proteins or host evasion systems) can cross from outside the cell into the nucleus and be expressed is particularly remarkable given the sophistication of the immune system in preventing infection by pathogens. As a result of the ease, low...

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Share to Immunotherapy and Immune Responses
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Share to Viral gastroenteritis research and epidemiology

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PMID: 26104452
DOI: 10.1128/microbiolspec.plas-0028-2014

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