Article
From Plasmids to Protection: A Review of DNA Vaccines Against Infectious Diseases
1 Jan 2006
Abstract excerpt
The field of DNA vaccine development began over 16 years ago with the observation that plasmid DNA could be injected into and expressed in vivo and drive adaptive immune responses. Since then, there has been great interest in developing this technology to create a new generation of vaccines with the ability to elicit both humoral and cellular immune responses from an inherently innocuous injection. However, DNA...
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