Article
DNA vaccines: A safe and efficient platform technology for responding to emerging infectious diseases
1 Sept 2009
Abstract excerpt
Traditionally vaccines are based on immunogens delivered as attenuated live microbes, inactivated pathogens, purified proteins, or virus-like particles. Newer generation vaccines are based on the delivery of genes encoding for a protein antigen that can be transcribed and translated by host cells. Despite current challenges to improve delivery and immunogenicity, DNA vaccination has several major advantages over...
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