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Article

MicroRNA-374b Suppresses Proliferation and Promotes Apoptosis in T-cell Lymphoblastic Lymphoma by Repressing AKT1 and Wnt-16

22 Jun 2015

Abstract excerpt

PURPOSE: Deregulation of microRNA (miRNA) has been extensively investigated in both Hodgkin and non-Hodgkin lymphomas (NHL); however, little is known about the roles of miRNAs in T-cell lymphoblastic lymphoma (T-LBL). The aim of the present study was to investigate the potential roles of miR-374b in the development and treatment of T-LBL. EXPERIMENTAL DESIGN: MiRCURY LNA array was used to generate a...

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PMID: 26100275
DOI: 10.1158/1078-0432.ccr-14-2947

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