Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

STAT3-mediated activation of microRNA cluster 17 92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphoma

23 Aug 2013

Abstract excerpt

Systemic anaplastic large cell lymphoma is a category of T-cell non-Hodgkin's lymphoma which can be further subdivided into two distinct entities (ALK(+) and ALK(-)) based on the presence or absence of ALK gene rearrangements. Among several pathways triggered by ALK signaling, constitutive activation of STAT3 is strictly required for ALK-mediated transformation and survival. Here we performed genome-wide microRNA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Circular RNAs in diseases
Share to Lymphoma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23975180
DOI: 10.3324/haematol.2013.088286

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

STAT3-mediated activation of microRNA cluster 17 92 promotes proliferation and survival of ALK-positive anaplastic large cell lymphomaPMID 23975180Read ↗

microRNA expression profiling identifies molecular signatures associated with anaplastic large cell lymphomaSemantic proximity Read ↗

The Long Non-Coding RNA MIR503HG Enhances Proliferation of Human ALK-Negative Anaplastic Large-Cell LymphomaSemantic proximity Read ↗

MicroRNA 96 Is a Post-Transcriptional Suppressor of Anaplastic Lymphoma Kinase ExpressionSemantic proximity Read ↗

miR-17-92 cluster-BTG2 axis regulates B-cell receptor signaling in mantle cell lymphomaSemantic proximity Read ↗

MicroRNA-374b Suppresses Proliferation and Promotes Apoptosis in T-cell Lymphoblastic Lymphoma by Repressing AKT1 and Wnt-16Semantic proximity Read ↗

A microRNA polycistron as a potential human oncogene.Semantic proximity Read ↗

The miR-17-92 microRNA cluster: a novel diagnostic tool in large B-cell malignanciesSemantic proximity Read ↗

miR-17~92 Promotes Progression of ABC-DLBCL Lymphoma via Regulation of Canonical NF-kB SignalingSemantic proximity Read ↗

Partial deletion of the ALK gene in ALK-positive anaplastic large cell lymphoma.Semantic proximity Read ↗

Ablation of oncogenic ALK is a viable therapeutic approach for anaplastic large-cell lymphomasSemantic proximity Read ↗

Alterations of microRNA and microRNA-regulated messenger RNA expression in germinal center B-cell lymphomas determined by integrative sequencing analysis.Semantic proximity Read ↗

The Myc-miR-17-92 axis amplifies B-cell receptor signaling via inhibition of ITIM proteins: a novel lymphomagenic feed-forward loopSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.