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MYC overexpression correlates with MYC amplification or translocation, and is associated with poor prognosis in mantle cell lymphoma

22 Jun 2015

Abstract excerpt

AIMS: We aimed to investigate MYC expression and chromosomal aberration in mantle cell lymphoma (MCL), and the clinical significance of these factors. METHODS AND RESULTS: Sixty-five patients with MCL, including 54 classic, nine blastoid and two pleomorphic variants, were enrolled. Expression of MYC, Ki67 and p53 was assessed by immunohistochemistry. MYC amplification or translocation was examined by fluorescence...

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PMID: 26100211
DOI: 10.1111/his.12760

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