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Article

Mutation scanning of the COQ2 gene in ethnic Chinese patients with multiple-system atrophy.

Neurobiology of aging - 1 Feb 2015

Chen Yong Ping, Zhao Bi, Cao Bei, Song Wei, Guo XiaoYan, Wei Qian-Qian, Yang Yuan, Yuan Li Xing, Shang Hui-Fang

Abstract excerpt

Multiple-system atrophy (MSA) is a fatal neurodegenerative disorder with unknown etiology. It is widely considered to be a nongenetic disorder, but accumulating evidence suggests that several genes are linked to MSA. Recently, functionally impaired variants in the coenzyme Q2 4-hydroxybenzoate polyprenyltransferase (COQ2) gene have been reported to increase the risk of MSA in familial and sporadic Japanese...

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Source

Identifiers

PMID: 25442117
DOI: 10.1016/j.neurobiolaging.2014.09.010

Genes

COQ2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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