Article
Role of the Ubiquitin-Proteasome Systems in the Biology and Virulence of Protozoan Parasites
1 Jan 2015
Abstract excerpt
In eukaryotic cells, proteasomes perform crucial roles in many cellular pathways by degrading proteins to enforce quality control and regulate many cellular processes such as cell cycle progression, signal transduction, cell death, immune responses, metabolism, protein-quality control, and development. The catalytic heart of these complexes, the 20S proteasome, is highly conserved in bacteria, yeast, and humans....
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