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Ubiquitination and the Proteasome as Drug Targets in Trypanosomatid Diseases

28 Jan 2021

Abstract excerpt

are responsible for debilitating diseases that affect millions of people worldwide. The numbers of drugs available to treat these diseases, Human African Trypanosomiasis, Chagas' disease and Leishmaniasis are very limited and existing treatments have substantial shortcomings in delivery method, efficacy and safety. The identification and validation of novel drug targets opens up new opportunities for the...

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PMID: 33732684
DOI: 10.3389/fchem.2020.630888

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