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More Than Just Cleaning: Ubiquitin-Mediated Proteolysis in Fungal Pathogenesis

10 Nov 2021

Abstract excerpt

Ubiquitin-proteasome mediated protein turnover is an important regulatory mechanism of cellular function in eukaryotes. Extensive studies have linked the ubiquitin-proteasome system (UPS) to human diseases, and an array of proteasome inhibitors have been successfully developed for cancer therapy. Although still an emerging field, research on UPS regulation of fungal development and virulence has been rapidly...

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PMID: 34858882
DOI: 10.3389/fcimb.2021.774613

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