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Combined parental obesity negatively impacts preimplantation mouse embryo development, kinetics, morphology and metabolism

18 Jun 2015

Abstract excerpt

STUDY QUESTION: Does combined parental obesity, both an obese mother and father, have a greater effect on mouse preimplantation embryo development and quality than single-parent obesity? SUMMARY ANSWER: Combined parental obesity causes a greater reduction in the blastocyst rate and a greater delay to the timing of key embryonic developmental events than single-parental obesity, as well as altering embryonic...

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PMID: 26089300
DOI: 10.1093/humrep/dev142

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