Article
Human embryos from overweight and obese women display phenotypic and metabolic abnormalities.
Human reproduction (Oxford, England) - 1 Jan 2015
Leary Christine, Leese Henry J, Sturmey Roger G
Abstract excerpt
STUDY QUESTION: Is the developmental timing and metabolic regulation disrupted in embryos from overweight or obese women? SUMMARY ANSWER: Oocytes from overweight or obese women are smaller than those from women of healthy weight, yet post-fertilization they reach the morula stage faster and, as blastocysts, show reduced glucose consumption and elevated endogenous triglyceride levels. WHAT IS KNOWN ALREADY: Female...
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