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Article

Clinical MRSA isolates from skin and soft tissue infections show increased in vitro production of phenol soluble modulins.

The Journal of infection - 1 Oct 2015

Berlon Nicholas R, Qi Robert, Sharma-Kuinkel Batu K, Joo Hwang-Soo, Park Lawrence P, George Dennis, Thaden Joshua T, Messina Julia A, Maskarinec Stacey A, Mueller-Premru Manica, Athan Eugene, Tattevin Pierre, Pericas Juan M, Woods Christopher W, Otto Michael, Fowler Vance G

Abstract excerpt

BACKGROUND: Phenol-soluble modulins (PSMs) are amphipathic, pro-inflammatory proteins secreted by most Staphylococcus aureus isolates. This study tested the hypothesis that in vitro PSM production levels are associated with specific clinical phenotypes. METHODS: 177 methicillin-resistant S. aureus (MRSA) isolates from infective endocarditis (IE), skin and soft tissue infection (SSTI), and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26079275
DOI: 10.1016/j.jinf.2015.06.005
PMCID: PMC4816458

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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