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Article

Rapid and accurate large-scale genotyping of duplicated genes and discovery of interlocus gene conversions.

Nature methods - 1 Sept 2013

Nuttle Xander, Huddleston John, O'Roak Brian J, Antonacci Francesca, Fichera Marco, Romano Corrado, Shendure Jay, Eichler Evan E

Abstract excerpt

Over 900 genes have been annotated within duplicated regions of the human genome, yet their functions and potential roles in disease remain largely unknown. One major obstacle has been the inability to accurately and comprehensively assay genetic variation for these genes in a high-throughput manner. We developed a sequencing-based method for rapid and high-throughput genotyping of duplicated genes using...

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Identifiers

PMID: 23892896
DOI: 10.1038/nmeth.2572
PMCID: PMC3985568

Genes

SRGAP2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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