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Article

Immunohistochemistry for BRAF V600E in the Differential Diagnosis of Hairy Cell Leukemia vs Other Splenic B-Cell Lymphomas.

American journal of clinical pathology - 1 Jul 2015

Turakhia Samir, Lanigan Christopher, Hamadeh Fatima, Swerdlow Steven H, Tubbs Raymond R, Cook James R

Abstract excerpt

OBJECTIVES: Recent reports have used immunohistochemistry (IHC) with a mutation-specific antibody to detect the BRAF V600E mutation, which is found in nearly all cases of hairy cell leukemia (HCL). To date, however, only a small number of non-HCL, splenic B-cell lymphomas have been examined by IHC. METHODS: We analyzed 121 cases, including 26 HCLs, 52 non-HCL splenic lymphomas, 22 chronic lymphocytic...

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Source

Identifiers

PMID: 26071465
DOI: 10.1309/AJCP5WVXJ2KTLODO

Genes

BRAF

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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