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Article

Prediction of complex human diseases from pathway-focused candidate markers by joint estimation of marker effects: case of chronic fatigue syndrome.

Human genomics - 11 Jun 2015

Bhattacharjee Madhuchhanda, Rajeevan Mangalathu S, Sillanpää Mikko J

Abstract excerpt

BACKGROUND: The current practice of using only a few strongly associated genetic markers in regression models results in generally low power in prediction or accounting for heritability of complex human traits. PURPOSE: We illustrate here a Bayesian joint estimation of single nucleotide polymorphism (SNP) effects principle to improve prediction of phenotype status from pathway-focused sets of SNPs. Chronic...

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Identifiers

PMID: 26063326
DOI: 10.1186/s40246-015-0030-6
PMCID: PMC4479222

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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