High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue.

doi:10.1093/infdis/jiv321

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Article

High Anti-Dengue Virus Activity of the OAS Gene Family Is Associated With Increased Severity of Dengue.

The Journal of infectious diseases - 15 Dec 2015

Simon-Loriere Etienne, Lin Ren-Jye, Kalayanarooj Sita Mint, Chuansumrit Ampaiwan, Casademont Isabelle, Lin Shyr-Yi, Yu Han-Pang, Lert-Itthiporn Worachart, Chaiyaratana Wathanee, Tangthawornchaikul Nattaya, Tangnararatchakit Kanchana, Vasanawathana Sirijitt, Chang Bi-Lan, Suriyaphol Prapat, Yoksan Sutee, Malasit Prida, Despres Philipe, Paul Richard, Lin Yi-Ling, Sakuntabhai Anavaj

Abstract excerpt

Dengue is a mosquito-borne viral disease that afflicts millions of individuals worldwide every year. Infection by any of the 4 dengue virus (DENV) serotypes can result in a spectrum of disease severity. We investigated the impact of variants of interferon-regulated innate immunity genes with a potent antiviral effect on the outcome of DENV infection. We compared the effect of OAS gene family variants on 2 DENV...

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Identifiers

PMID: 26063222
DOI: 10.1093/infdis/jiv321

Genes

OAS1
OAS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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