Regulation of cholesteryl ester transfer protein expression by upstream polymorphisms: reduced expression associated with rs247616.

doi:10.1097/FPC.0000000000000151

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Article

Regulation of cholesteryl ester transfer protein expression by upstream polymorphisms: reduced expression associated with rs247616.

Pharmacogenetics and genomics - 1 Aug 2015

Suhy Adam, Hartmann Katherine, Papp Audrey C, Wang Danxin, Sadee Wolfgang

Abstract excerpt

BACKGROUND: Cholesteryl ester transfer protein (CETP) is involved in reverse cholesterol transport by exchanging cholesteryl esters for triglycerides between high-density lipoprotein and low-density lipoprotein particles, effectively decreasing high-density lipoprotein cholesterol levels. Variants within a large haplotype block upstream of CETP (rs247616, rs173539) have been shown to be significantly associated...

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PMID: 26061659
DOI: 10.1097/FPC.0000000000000151
PMCID: PMC4499003

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CETP

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