Article
Hypertension-related alterations in white matter microstructure detectable in middle age.
Hypertension (Dallas, Tex. : 1979) - 1 Aug 2015
McEvoy Linda K, Fennema-Notestine Christine, Eyler Lisa T, Franz Carol E, Hagler Donald J, Lyons Michael J, Panizzon Matthew S, Rinker Daniel A, Dale Anders M, Kremen William S
Abstract excerpt
Most studies examining associations between hypertension and brain white matter microstructure have focused on older adults or on cohorts with a large age range. Because hypertension effects on the brain may vary with age, it is important to focus on middle age, when hypertension becomes more prevalent. We used linear mixed-effect models to examine differences in white matter diffusion metrics as a function of...
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