Article
Association of TNF-α gene promoter region polymorphisms in bovine leukemia virus (BLV)-infected cattle with different proviral loads.
Archives of virology - 1 Aug 2015
Lendez Pamela Anahi, Passucci Juan Antonio, Poli Mario Andres, Gutierrez Silvina Elena, Dolcini Guillermina Laura, Ceriani Maria Carolina
Abstract excerpt
Tumor necrosis factor alpha (TNF-α) is a pleiotropic cytokine involved in the immune response against viral and other infections. Its expression levels are affected by a polymorphism in the promoter region of the gene. Bovine leukemia virus is a retrovirus that infects cattle and develops two different infection profiles in the host. One profile is characterized by a high number of proviral copies integrated into...
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