Article
Candidate genes for Parkinson disease: Lessons from pathogenesis.
Clinica chimica acta; international journal of clinical chemistry - 20 Sept 2015
De Rosa Priscilla, Marini Elettra Sara, Gelmetti Vania, Valente Enza Maria
Abstract excerpt
Parkinson disease (PD) is a multifactorial neurodegenerative disease characterized by the progressive loss of specific neuronal populations and accumulation of Lewy bodies in the brain, leading to motor and non-motor symptoms. In a small subset of patients, PD is dominantly or recessively inherited, while a number of susceptibility genetic loci have been identified through genome wide association studies. The...
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