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Article

Evidence for Clinical Implementation of Pharmacogenomics in Cardiac Drugs.

Mayo Clinic proceedings - 1 Jun 2015

Kaufman Amy L, Spitz Jared, Jacobs Michael, Sorrentino Matthew, Yuen Shennin, Danahey Keith, Saner Donald, Klein Teri E, Altman Russ B, Ratain Mark J, O'Donnell Peter H

Abstract excerpt

OBJECTIVE: To comprehensively assess the pharmacogenomic evidence of routinely used drugs for clinical utility. METHODS: Between January 2, 2011, and May 31, 2013, we assessed 71 drugs by identifying all drug/genetic variant combinations with published clinical pharmacogenomic evidence. Literature supporting each drug/variant pair was assessed for study design and methods, outcomes, statistical significance, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Outcome Assessment, Health Care

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Share to Polymorphism, Genetic

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Source

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Identifiers

PMID: 26046407
DOI: 10.1016/j.mayocp.2015.03.016
PMCID: PMC4475352

Genes

VKORC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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