Article
Bladder and gastric metastases from lung adenocarcinoma harboring codon 13 KRAS mutation: a case report with unusual clinical outcome.
Tumori - 9 Sept 2015
Galetta Domenico, Catino Annamaria, Misino Andrea, De Ceglie Antonella, Logroscino Antonio, Simone Giovanni, Natalicchio Maria Iole
Abstract excerpt
AIMS AND BACKGROUND: Gastric and bladder metastases are rare in non-small-cell lung cancer (NSCLC) and the differential diagnosis with primary tumors requires an in-depth examination. KRAS gene mutations are the main oncogenic driver of lung adenocarcinoma in Caucasian patients, occurring in 25%-30% of cases, but their prognostic and predictive role is complex and not fully clarified. KRAS mutations in lung...
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