Article
Whole-Genome Resequencing of Experimental Populations Reveals Polygenic Basis of Egg-Size Variation in Drosophila melanogaster.
Molecular biology and evolution - 1 Oct 2015
Jha Aashish R, Miles Cecelia M, Lippert Nodia R, Brown Christopher D, White Kevin P, Kreitman Martin
Abstract excerpt
Complete genome resequencing of populations holds great promise in deconstructing complex polygenic traits to elucidate molecular and developmental mechanisms of adaptation. Egg size is a classic adaptive trait in insects, birds, and other taxa, but its highly polygenic architecture has prevented high-resolution genetic analysis. We used replicated experimental evolution in Drosophila melanogaster and...
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