Article
Emerging platforms using liquid biopsy to detect EGFR mutations in lung cancer.
Expert review of molecular diagnostics - 1 Jan 2015
Lin Chien-Chung, Huang Wei-Lun, Wei Fang, Su Wu-Chou, Wong David T
Abstract excerpt
Advances in target therapies for lung cancer have enabled detection of gene mutations, specifically those of EGFR. Assays largely depend on the acquisition of tumor tissue biopsy, which is invasive and may not reflect the genomic profile of the tumor at treatment due to tumor heterogeneity or changes that occur during treatment through acquired resistance. Liquid biopsy, a blood test that detects evidence of...
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