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Article

Are liquid biopsies a surrogate for tissue EGFR testing?

Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 2018

Goldman J W, Noor Z S, Remon J, Besse B, Rosenfeld N

Abstract excerpt

Molecular profiling has changed the treatment landscape in advanced non-small-cell lung cancer. Accurately identifying the tumours that harbour sensitizing EGFR mutations, the most common targetable molecular alteration, as well as those with acquired resistance mutations (e.g. T790M) on treatment is a high clinical priority. The current clinical gold standard is genotyping of tumour specimens. However, the...

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Identifiers

PMID: 29462257
DOI: 10.1093/annonc/mdx706

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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