Article
Influenza virus reassortment occurs with high frequency in the absence of segment mismatch.
PLoS pathogens - 1 Jan 2013
Marshall Nicolle, Priyamvada Lalita, Ende Zachary, Steel John, Lowen Anice C
Abstract excerpt
Reassortment is fundamental to the evolution of influenza viruses and plays a key role in the generation of epidemiologically significant strains. Previous studies indicate that reassortment is restricted by segment mismatch, arising from functional incompatibilities among components of two viruses. Additional factors that dictate the efficiency of reassortment remain poorly characterized. Thus, it is unclear...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
