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Article

Calorie seeking, but not hedonic response, contributes to hyperphagia in a mouse model for Prader-Willi syndrome.

The European journal of neuroscience - 1 Aug 2015

Davies Jennifer R, Humby Trevor, Dwyer Dominic M, Garfield Alastair S, Furby Hannah, Wilkinson Lawrence S, Wells Timothy, Isles Anthony R

Abstract excerpt

Prader-Willi syndrome (PWS) is a neurodevelopmental disorder caused by deletion or inactivation of paternally expressed imprinted genes on human chromosome 15q11-q13, the most recognised feature of which is hyperphagia. This is thought to arise as a consequence of abnormalities in both the physiological drive for food and the rewarding properties of food. Although a number of mouse models for PWS exist, the...

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Source

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Identifiers

PMID: 26040449
DOI: 10.1111/ejn.12972
PMCID: PMC4949663

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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