Article
MiRNA-Related SNPs and Risk of Esophageal Adenocarcinoma and Barrett's Esophagus: Post Genome-Wide Association Analysis in the BEACON Consortium.
PloS one - 1 Jan 2015
Buas Matthew F, Onstad Lynn, Levine David M, Risch Harvey A, Chow Wong-Ho, Liu Geoffrey, Fitzgerald Rebecca C, Bernstein Leslie, Ye Weimin, Bird Nigel C, Romero Yvonne, Casson Alan G, Corley Douglas A, Shaheen Nicholas J, Wu Anna H, Gammon Marilie D, Reid Brian J, Hardie Laura J, Peters Ulrike, Whiteman David C, Vaughan Thomas L
Abstract excerpt
Incidence of esophageal adenocarcinoma (EA) has increased substantially in recent decades. Multiple risk factors have been identified for EA and its precursor, Barrett's esophagus (BE), such as reflux, European ancestry, male sex, obesity, and tobacco smoking, and several germline genetic variants were recently associated with disease risk. Using data from the Barrett's and Esophageal Adenocarcinoma Consortium...
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