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Article

High frequency of the 23S rRNA A2058G mutation of Treponema pallidum in Shanghai is associated with a current strategy for the treatment of syphilis.

Emerging microbes & infections - 1 Feb 2015

Lu Haikong, Li Kang, Gong Weimin, Yan Limeng, Gu Xin, Chai Ze, Guan Zhifang, Zhou Pingyu

Abstract excerpt

The preferred drugs for the treatment of syphilis, benzathine and procaine penicillin, have not been available in Shanghai for many years, and currently, the incidence of syphilis is increasing. Alternative antibiotics for patients with syphilis during the benzathine and procaine penicillin shortage include macrolides. The failure of macrolide treatment in syphilis patients has been reported in Shanghai, but the...

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Identifiers

PMID: 26038763
DOI: 10.1038/emi.2015.10
PMCID: PMC4345286

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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