Article
Multicentre surveillance of prevalence of the 23S rRNA A2058G and A2059G point mutations and molecular subtypes of Treponema pallidum in Taiwan, 2009-2013.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Aug 2014
Wu B-R, Yang C-J, Tsai M-S, Lee K-Y, Lee N-Y, Huang W-C, Wu H, Lee C-H, Chen T-C, Ko W-C, Lin H-H, Lu P-L, Chen Y-H, Liu W-C, Yang S-P, Wu P-Y, Su Y-C, Hung C-C, Chang S-Y
Abstract excerpt
Resistance mutations A2058G and A2059G, within the 23S rRNA gene of Treponema pallidum, have been reported to cause treatment failures in patients receiving azithromycin for syphilis. Genotyping of T. pallidum strains sequentially isolated from patients with recurrent syphilis is rarely performed. From September 2009 to August 2013, we collected 658 clinical specimens from 375 patients who presented with syphilis...
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