Article
Association of Antibodies to Interferon-Inducible Protein-16 With Markers of More Severe Disease in Primary Sjögren's Syndrome.
Arthritis care & research - 1 Feb 2016
Baer Alan N, Petri Michelle, Sohn Jungsan, Rosen Antony, Casciola-Rosen Livia
Abstract excerpt
OBJECTIVE: Interferon-inducible protein-16 (IFI16) is an intracellular DNA receptor involved in innate immunity. We evaluated the frequency, phenotypic characteristics, and clinical associations of anti-IFI16 antibodies in patients with primary Sjögren's syndrome (SS), and quantitated expression levels of IFI16 in SS and control salivary gland lysates. METHODS: Anti-IFI16 antibodies were assayed by enzyme-linked...
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