Article
Recent Evolution in Rattus norvegicus Is Shaped by Declining Effective Population Size.
Molecular biology and evolution - 1 Oct 2015
Deinum Eva E, Halligan Daniel L, Ness Rob W, Zhang Yao-Hua, Cong Lin, Zhang Jian-Xu, Keightley Peter D
Abstract excerpt
The brown rat, Rattus norvegicus, is both a notorious pest and a frequently used model in biomedical research. By analyzing genome sequences of 12 wild-caught brown rats from their presumed ancestral range in NE China, along with the sequence of a black rat, Rattus rattus, we investigate the selective and demographic forces shaping variation in the genome. We estimate that the recent effective population size...
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