Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of Muscle-Specific MiRNA 206 in the Progression of Disease in a Murine SMA Model

1 Jun 2015

Abstract excerpt

Spinal muscular atrophy (SMA) is a severe neuromuscular disease, the most common in infancy, and the third one among young people under 18 years. The major pathological landmark of SMA is a selective degeneration of lower motor neurons, resulting in progressive skeletal muscle denervation, atrophy, and paralysis. Recently, it has been shown that specific or general changes in the activity of ribonucleoprotein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Muscle Physiology and Disorders
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26030275
DOI: 10.1371/journal.pone.0128560

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of Muscle-Specific MiRNA 206 in the Progression of Disease in a Murine SMA ModelPMID 26030275Read ↗

Pathogenesis and therapeutic targets in spinal muscular atrophy (SMA).Semantic proximity Read ↗

Spinal muscular atrophy: recent advances and future prospects.Semantic proximity Read ↗

mi RNA in spinal muscular atrophy pathogenesis and therapySemantic proximity Read ↗

Dysregulation of the Tweak/Fn14 pathway in skeletal muscle of spinal muscular atrophy miceSemantic proximity Read ↗

At the "junction" of spinal muscular atrophy pathogenesis: the role of neuromuscular junction dysfunction in SMA disease progression.Semantic proximity Read ↗

Dysregulation of Muscle-Specific MicroRNAs as Common Pathogenic Feature Associated with Muscle Atrophy in ALS, SMA and SBMA: Evidence from Animal Models and Human PatientsSemantic proximity Read ↗

The Actin Cytoskeleton in SMA and ALS: How Does It Contribute to Motoneuron Degeneration?Semantic proximity Read ↗

Whole-transcriptome sequencing in neural and non-neural tissues of a mouse model identifies miR-34a as a key regulator in SMA pathogenesisSemantic proximity Read ↗

Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophySemantic proximity Read ↗

miRNA malfunction causes spinal motor neuron diseaseSemantic proximity Read ↗

Combining SMN2 splicing modifiers with HDAC6 inhibition greatly improves muscle function and survival in Spinal Muscular AtrophySemantic proximity Read ↗

A critical smn threshold in mice dictates onset of an intermediate spinal muscular atrophy phenotype associated with a distinct neuromuscular junction pathology.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.