GATA2 and secondary mutations in familial myelodysplastic syndromes and pediatric myeloid malignancies

Abstract excerpt

GATA2 , a member of the GATA transcription factor family, plays a critical role in hematopoiesis,[1][1] vascular[2][2] and neural development. Mutations in the exons and intron 5 of this gene have been identified as the cause of several hematologic disorders.[3][3] GATA2 -related disorders include

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