Article
Donor-derived MDS/AML in families with germline GATA2 mutation
19 Sept 2018
Abstract excerpt
TO THE EDITOR: GATA2 encodes a zinc-finger transcription factor that is required for proliferation and survival of hematopoietic stem cells.[1][1] First described in 2011, germline heterozygous mutations in GATA2 lead to haploinsufficiency[2][2] and are associated with bone marrow failure,
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