Article
The Human Pathogen Streptococcus pyogenes Releases Lipoproteins as Lipoprotein-rich Membrane Vesicles.
Molecular & cellular proteomics : MCP - 1 Aug 2015
Biagini Massimiliano, Garibaldi Manuela, Aprea Susanna, Pezzicoli Alfredo, Doro Francesco, Becherelli Marco, Taddei Anna Rita, Tani Chiara, Tavarini Simona, Mora Marirosa, Teti Giuseppe, D'Oro Ugo, Nuti Sandra, Soriani Marco, Margarit Immaculada, Rappuoli Rino, Grandi Guido, Norais Nathalie
Abstract excerpt
Bacterial lipoproteins are attractive vaccine candidates because they represent a major class of cell surface-exposed proteins in many bacteria and are considered as potential pathogen-associated molecular patterns sensed by Toll-like receptors with built-in adjuvanticity. Although Gram-negative lipoproteins have been extensively characterized, little is known about Gram-positive lipoproteins. We isolated from...
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