Article
Subculture affects the phenotypic expression of human periodontal ligament cells and their response to fibroblast growth factor-2 and bone morphogenetic protein-7 in vitro.
Journal of periodontal research - 1 Oct 2008
Lossdörfer S, Fiekens D, Salik M I, Götz W, Jäger A
Abstract excerpt
BACKGROUND AND OBJECTIVE: Although periodontal ligament cells display several osteoblastic traits, their phenotypic expression is still not well established. It remains a matter of debate whether they resemble a terminally differentiated cell type or an intermediate maturation state that potentially can be directed towards a fibroblastic or an osteoblastic phenotype. MATERIAL AND METHODS: To explore the...
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