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Article

Three-dimensional spheroid culture promotes odonto/osteoblastic differentiation of dental pulp cells.

Archives of oral biology - 1 Mar 2014

Yamamoto Mioko, Kawashima Nobuyuki, Takashino Nami, Koizumi Yu, Takimoto Koyo, Suzuki Noriyuki, Saito Masahiro, Suda Hideaki

Abstract excerpt

OBJECTIVE: Three-dimensional (3D) spheroid culture is a method for creating 3D aggregations of cells and their extracellular matrix without a scaffold mimicking the actual tissues. The aim of this study was to evaluate the effects of 3D spheroid culture on the phenotype of immortalized mouse dental papilla cells (MDPs) that have the ability to differentiate into odontoblasts. METHODS: We cultured MDPs for 1, 3,...

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Source

Identifiers

PMID: 24581854
DOI: 10.1016/j.archoralbio.2013.12.006

Genes

DMP1
LOX

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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