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Article

Myocardial performance and adaptive energy pathways in a torpid mammalian hibernator.

American journal of physiology. Regulatory, integrative and comparative physiology - 15 Aug 2015

Heinis Frazer I, Vermillion Katie L, Andrews Matthew T, Metzger Joseph M

Abstract excerpt

The hearts of mammalian hibernators maintain contractile function in the face of severe environmental stresses during winter heterothermy. To enable survival in torpor, hibernators regulate the expression of numerous genes involved in excitation-contraction coupling, metabolism, and stress response pathways. Understanding the basis of this transition may provide new insights into treatment of human cardiac...

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Identifiers

PMID: 26017496
DOI: 10.1152/ajpregu.00365.2014
PMCID: PMC4538225

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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