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Article

Identification of a putative quantitative trait nucleotide in guanylate binding protein 5 for host response to PRRS virus infection.

BMC genomics - 28 May 2015

Koltes James E, Fritz-Waters Eric, Eisley Chris J, Choi Igseo, Bao Hua, Kommadath Arun, Serão Nick V L, Boddicker Nicholas J, Abrams Sam M, Schroyen Martine, Loyd Hyelee, Tuggle Chris K, Plastow Graham S, Guan Leluo, Stothard Paul, Lunney Joan K, Liu Peng, Carpenter Susan, Rowland Robert R R, Dekkers Jack C M, Reecy James M

Abstract excerpt

BACKGROUND: Previously, we identified a major quantitative trait locus (QTL) for host response to Porcine Respiratory and Reproductive Syndrome virus (PRRSV) infection in high linkage disequilibrium (LD) with SNP rs80800372 on Sus scrofa chromosome 4 (SSC4). RESULTS: Within this QTL, guanylate binding protein 5 (GBP5) was differentially expressed (DE) (p < 0.05) in blood from AA versus AB rs80800372 genotyped...

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Source

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Identifiers

PMID: 26016888
DOI: 10.1186/s12864-015-1635-9
PMCID: PMC4446061

Genes

GBP5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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