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Article

Genetic architecture of gene expression underlying variation in host response to porcine reproductive and respiratory syndrome virus infection.

Scientific reports - 10 Apr 2017

Kommadath Arun, Bao Hua, Choi Igseo, Reecy James M, Koltes James E, Fritz-Waters Elyn, Eisley Chris J, Grant Jason R, Rowland Robert R R, Tuggle Christopher K, Dekkers Jack C M, Lunney Joan K, Guan Le Luo, Stothard Paul, Plastow Graham S

Abstract excerpt

It has been shown that inter-individual variation in host response to porcine reproductive and respiratory syndrome (PRRS) has a heritable component, yet little is known about the underlying genetic architecture of gene expression in response to PRRS virus (PRRSV) infection. Here, we integrated genome-wide genotype, gene expression, viremia level, and weight gain data to identify genetic polymorphisms that are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28393889
DOI: 10.1038/srep46203
PMCID: PMC5385538

Genes

CCHCR1
CMPK2
GBP5
GBP6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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