Article
Hypercoagulability in adolescent girls on oral contraceptives-global coagulation profile and estrogen receptor polymorphisms.
American journal of hematology - 1 Aug 2015
Zia Ayesha, Callaghan Michael U, Callaghan Joseph H, Sawni Anju, Bartlett Heather, Backos Alcesa, Marshall Sharon, Chitlur Meera, Rajpurkar Madhvi
Abstract excerpt
Oral contraceptive (OCP) induced changes on coagulation are complex with high inter-individual variability. The precise reason for differences in this variability is unknown. We hypothesized that global coagulation assays better delineate these changes and variability in hypercoagulability may be the result of differences in estrogen metabolism and thrombophilia. Fifty-two adolescents initiating OCPs were...
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