Article
The identification of loci for polydactyly in chickens using a genome-wide association study.
Gene - 1 Sept 2015
Sheng Xihui, Chen Yu, Jia Yaxiong, Qi Xiaolong, Feng Yun, Huang Zhen, Guo Yong
Abstract excerpt
Polydactyly is a commonly observed limb malformation in humans and other vertebrates. The Beijing-You chicken expressing the polydactyly phenotype provides an opportunity to investigate the potential cause for polydactyly. Here we extensively exploited genetic determinants of the chicken polydactyly in a genome wide association study using over 580,000 SNPs characterized in a Beijing-You × Lohmann F1 cross,...
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