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Article

Single nucleotide polymorphisms in the chicken Lmbr1 gene are associated with chicken polydactyly.

Gene - 7 Jun 2006

Huang Yan Qun, Deng Xue Mei, Du Zhi Qiang, Qiu Xiangpin, Du Xiaohui, Chen Wen, Morisson Mireille, Leroux Sophie, Ponce de Léon F Abel, Da Yang, Li Ning

Abstract excerpt

Polydactyly is a common malformation of vertebrate limbs. Preaxial polydactyly (PPD) has been mapped in human, mouse and chicken to the syntenic region of human 7q36. Lmbr1 was thought as the critical candidate gene for human and mouse PPD. To understand the molecular mechanism underlying chicken polydactyly, we have cloned the open reading frame (ORF) of chicken Lmbr1, which contains 1467 nucleotides. Within...

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PMID: 16650944
DOI: 10.1016/j.gene.2005.07.047

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